BDBM50071718 CHEMBL421722::Cyanoguanidine derivative

SMILES [O-][n+]1cccc(CNC(=NC#N)N2CCN(CC2)C2c3ccc(Cl)cc3SCc3cccnc23)c1

InChI Key InChIKey=KTWBJQVQJFNIIQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071718   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50071718(CHEMBL421722 | Cyanoguanidine derivative)
Affinity DataIC50:  140nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]-farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed