BDBM50071718 CHEMBL421722::Cyanoguanidine derivative
SMILES [O-][n+]1cccc(CNC(=NC#N)N2CCN(CC2)C2c3ccc(Cl)cc3SCc3cccnc23)c1
InChI Key InChIKey=KTWBJQVQJFNIIQ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50071718
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:In vitro FPT potency by measuring the ability to inhibit the transfer of [3H]-farnesyl from farnesyl pyrophosphate to H-Ras-CLVS.More data for this Ligand-Target Pair