BDBM50071745 CHEMBL403317::Compound NMB::Gly-Asn-Leu-Trp-Ala-Thr-Gly-His-Phe-Met-NH2(Neuromedin B)::NMB

SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)CN)[C@@H](C)O)C(N)=O

InChI Key InChIKey=YPFNACALNKVZNK-MFNIMNRCSA-N

Data  5 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50071745   

TargetNeuromedin-B receptor(Homo sapiens (Human))
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071745(CHEMBL403317 | Compound NMB | Gly-Asn-Leu-Trp-Ala-...)
Affinity DataKi:  0.0680nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071745(CHEMBL403317 | Compound NMB | Gly-Asn-Leu-Trp-Ala-...)
Affinity DataKi:  0.550nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071745(CHEMBL403317 | Compound NMB | Gly-Asn-Leu-Trp-Ala-...)
Affinity DataKi:  56nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide(Homo sapiens (Human))
National Institutes Of Health

Curated by PDSP Ki Database
LigandPNGBDBM50071745(CHEMBL403317 | Compound NMB | Gly-Asn-Leu-Trp-Ala-...)
Affinity DataKi:  97nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
National Institutes Of Health

Curated by PDSP Ki Database
LigandPNGBDBM50071745(CHEMBL403317 | Compound NMB | Gly-Asn-Leu-Trp-Ala-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071745(CHEMBL403317 | Compound NMB | Gly-Asn-Leu-Trp-Ala-...)
Affinity DataEC50:  120nMAssay Description:Effective concentration required against nueromedin B receptor (NMB-R) in CHO cells by using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
National Institutes Of Health

Curated by PDSP Ki Database
LigandPNGBDBM50071745(CHEMBL403317 | Compound NMB | Gly-Asn-Leu-Trp-Ala-...)
Affinity DataEC50:  4.50E+3nMAssay Description:Effective concentration required against human bombesin receptor 3 (BRS-3) in CHO cells by using FLIPR assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM50071745(CHEMBL403317 | Compound NMB | Gly-Asn-Leu-Trp-Ala-...)
Affinity DataEC50:  41nMAssay Description:Effective concentration required against gastrin releasing peptide receptor (GRP-R) in CHO cells by using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed