BDBM50071885 4-[2-(4-Chloro-phenyl)-5-(4-fluoro-phenyl)-3H-imidazol-4-yl]-pyridine::CHEMBL314238

SMILES Fc1ccc(cc1)-c1[nH]c(nc1-c1ccncc1)-c1ccc(Cl)cc1

InChI Key InChIKey=BYRKVDOSQUAVAB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50071885   

TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50071885(4-[2-(4-Chloro-phenyl)-5-(4-fluoro-phenyl)-3H-imid...)
Affinity DataIC50:  3.20E+3nMAssay Description:Affinity for human glucagon receptor in presence of Mg2+More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Rattus norvegicus)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50071885(4-[2-(4-Chloro-phenyl)-5-(4-fluoro-phenyl)-3H-imid...)
Affinity DataIC50:  80nMAssay Description:Inhibitory potency evaluated against rat p38 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50071885(4-[2-(4-Chloro-phenyl)-5-(4-fluoro-phenyl)-3H-imid...)
Affinity DataIC50:  400nMAssay Description:Binding affinity towards human glucagon receptor in absence of Mg2+ expressed as IC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50071885(4-[2-(4-Chloro-phenyl)-5-(4-fluoro-phenyl)-3H-imid...)
Affinity DataIC50:  80nMAssay Description:Binding affinity towards human Mitogen-activated protein kinase p38 expressed as IC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50071885(4-[2-(4-Chloro-phenyl)-5-(4-fluoro-phenyl)-3H-imid...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human glucagon receptor expressed in CHO cell membranes by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails Article