BDBM50072209 3-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydroxy-ethoxy)-6-methoxy-quinazolin-2-ylamino]-propan-1-ol::CHEMBL97785

SMILES COc1cc2c(nc(NCCCO)nc2cc1OCCO)-c1cc(OCC2CC2)cc(OCC2CC2)c1

InChI Key InChIKey=FQHZXMKFQOKAPD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50072209   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072209(3-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)
Affinity DataIC50:  340nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072209(3-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)
Affinity DataIC50:  230nMAssay Description:Evaluated for its ability to inhibit PDE4D.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50072209(3-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)
Affinity DataIC50:  200nMAssay Description:Evaluated for the inhibition of [3H]rolipram binding to membrane-bound PDE4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072209(3-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)
Affinity DataIC50:  430nMAssay Description:Evaluated for its ability to inhibit PDE3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072209(3-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)
Affinity DataIC50:  500nMAssay Description:Evaluated for its ability to inhibit PDE4A.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed