BDBM50072260 (Z)-4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-but-2-enoic acid::4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-but-2-enoic acid (0.2H2O)::CHEMBL22480

SMILES OC(=O)C(=O)CC(=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=KKFZLKBJSYLDKE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072260   

TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072260((Z)-4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-but-2-...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of rat liver KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072260((Z)-4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-but-2-...)
Affinity DataIC50:  950nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072260((Z)-4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-but-2-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Kynurenine-3-hydroxylase enzyme isolated from the rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed