BDBM50072400 4-{3-[4-(4-Fluoro-phenyl)-5-(2-methoxy-pyrimidin-4-yl)-imidazol-1-yl]-propyl}-morpholine::CHEMBL14318::D3RKN_121

SMILES COc1nccc(n1)-c1c(ncn1CCCN1CCOCC1)-c1ccc(F)cc1

InChI Key InChIKey=UJPJYIXFJSSTRL-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072400   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50072400(4-{3-[4-(4-Fluoro-phenyl)-5-(2-methoxy-pyrimidin-4...)
Affinity DataIC50:  300nMAssay Description:Inhibitory concentration against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM50072400(4-{3-[4-(4-Fluoro-phenyl)-5-(2-methoxy-pyrimidin-4...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2025More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072400(4-{3-[4-(4-Fluoro-phenyl)-5-(2-methoxy-pyrimidin-4...)
Affinity DataIC50:  300nMAssay Description:Compound was tested for inhibition of p38 MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed