BDBM50072672 CHEMBL3410056
SMILES COCCN(C(=O)Nc1ccc(cc1F)-c1ncnc2[nH]c(C)c(C)c12)c1ccc(Cl)cc1
InChI Key InChIKey=OBXKCXDQQXDOSZ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50072672
Affinity DataIC50: 250nMAssay Description:Inhibition of Limk1 in rat A7r5 cells assessed as reduction in cofilin phosphorylation by Western blot methodMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human JNK3 using ATF2 substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human ROCK2 using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK peptide substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair