BDBM50072732 CHEMBL3410047

SMILES COc1cccc(c1)N(CCO)C(=O)Nc1ccc(cc1)-c1ncnc2[nH]cc(C)c12

InChI Key InChIKey=PNAOPOALRFDVMT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072732   

TargetLIM domain kinase 1(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50072732(CHEMBL3410047)
Affinity DataIC50:  100nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50072732(CHEMBL3410047)
Affinity DataIC50:  4.32E+3nMAssay Description:Inhibition of human ROCK1 using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK peptide substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50072732(CHEMBL3410047)
Affinity DataIC50:  3.22E+3nMAssay Description:Inhibition of human ROCK2 using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK peptide substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed