BDBM50072816 2,6-Dimethyl-4-[2-(2-nitrooxy-ethoxy)-phenyl]-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester::CHEMBL358157

SMILES COC([O-])=C1C(C(C(=[OH+])OC)=C(C)N=C1C)c1ccccc1OCCO[N+]([O-])=O

InChI Key InChIKey=OEMOFQQSFOYXJB-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072816   

TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universit£ degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50072816(2,6-Dimethyl-4-[2-(2-nitrooxy-ethoxy)-phenyl]-1,4-...)
Affinity DataKi:  38nMAssay Description:Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universit£ degli Studi di Torino

Curated by ChEMBL
LigandPNGBDBM50072816(2,6-Dimethyl-4-[2-(2-nitrooxy-ethoxy)-phenyl]-1,4-...)
Affinity DataIC50:  85nMAssay Description:Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed