BDBM50073027 8-Chloro-2-{2-[4-(2-chloro-phenyl)-piperazin-1-yl]-ethylamino}-6-methyl-6H-1,6,7,9a-tetraaza-fluoren-5-one::CHEMBL49851

SMILES Cn1nc(Cl)c2cn3nc(NCCN4CCN(CC4)c4ccccc4Cl)ccc3c2c1=O

InChI Key InChIKey=RORFUFVFDXKMOM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50073027   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50073027(8-Chloro-2-{2-[4-(2-chloro-phenyl)-piperazin-1-yl]...)
Affinity DataKi:  5.93nMAssay Description:The compound was tested for binding affinity on [3H]- prazosin as specific ligand on Human cloned alpha-1A adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50073027(8-Chloro-2-{2-[4-(2-chloro-phenyl)-piperazin-1-yl]...)
Affinity DataKi:  11.9nMAssay Description:The compound was tested for binding affinity on [3H]- prazosin as specific ligand on Human cloned alpha-1D adrenergic receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50073027(8-Chloro-2-{2-[4-(2-chloro-phenyl)-piperazin-1-yl]...)
Affinity DataKi:  13.6nMAssay Description:The compound was tested for binding affinity on [3H]- prazosin as specific ligand on Human cloned alpha-1B adrenergic receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50073027(8-Chloro-2-{2-[4-(2-chloro-phenyl)-piperazin-1-yl]...)
Affinity DataKi:  56.5nMAssay Description:The compound was tested for binding affinity on [3H]-8-OH-DPAT as specific ligand on 5-hydroxytryptamine 1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed