BDBM50073622 2-Dipropylamino-1,2,3,4-tetrahydro-naphthalene-1,8-diol::7,7-Bis-(3-amino-propyl)-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL146942

SMILES NCCCC1(CCCN)CCc2cccc(O)c2C1

InChI Key InChIKey=YMYPUTRJEDYPAQ-UHFFFAOYSA-N

Data  6 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50073622   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50073622(2-Dipropylamino-1,2,3,4-tetrahydro-naphthalene-1,8...)
Affinity DataKi:  2nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A human cloned receptors in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50073622(2-Dipropylamino-1,2,3,4-tetrahydro-naphthalene-1,8...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity against 5-hydroxytryptamine 7 human receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50073622(2-Dipropylamino-1,2,3,4-tetrahydro-naphthalene-1,8...)
Affinity DataKi:  126nMAssay Description:Binding affinity against 5-hydroxytryptamine 6 human cloned receptors in HeLa cells using [3H]LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50073622(2-Dipropylamino-1,2,3,4-tetrahydro-naphthalene-1,8...)
Affinity DataKi:  316nMAssay Description:Binding affinity against human 5-hydroxytryptamine 1B receptor cloned receptors in CHO cells using [3H]5-CT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50073622(2-Dipropylamino-1,2,3,4-tetrahydro-naphthalene-1,8...)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor human cloned receptors in HEK 293 cells using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50073622(2-Dipropylamino-1,2,3,4-tetrahydro-naphthalene-1,8...)
Affinity DataKi:  1.26E+4nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptor human cloned receptors in HEK 293 cells using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50073622(2-Dipropylamino-1,2,3,4-tetrahydro-naphthalene-1,8...)
Affinity DataIC50:  2.5nMAssay Description:In vitro inhibition of [3H]-8-OH-DPAT binding to rat 5-HT 1a receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed