BDBM50073701 2'-hexyl-5'-methylspiro[cyclopentane-1,7'-(4',5',7',8'-tetrahydro-3'H-imidazo[2,1-b]purine)]-4'-one::CHEMBL18965

SMILES CCCCCCc1nc2N3CC4(CCCC4)N=C3N(C)C(=O)c2[nH]1

InChI Key InChIKey=RSBCLMHCVBZLIE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50073701   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073701(2'-hexyl-5'-methylspiro[cyclopentane-1,7'-(4',5',7...)
Affinity DataIC50:  11nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific Phosphodiesterase 5 (PDE5) of bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073701(2'-hexyl-5'-methylspiro[cyclopentane-1,7'-(4',5',7...)
Affinity DataIC50:  1.50E+4nMAssay Description:Optimum inhibitory concentration required to inhibit cGMP specific phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073701(2'-hexyl-5'-methylspiro[cyclopentane-1,7'-(4',5',7...)
Affinity DataIC50:  14nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed