BDBM50074166 CHEMBL349390::N-{4-[({(S)-1-[2-(5-[1,2,4]Triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amino)-methyl]-phenyl}-acetamide

SMILES CC(=O)Nc1ccc(CNC[C@@H]2CCN(CCc3c[nH]c4ccc(cc34)-n3cnnc3)C2)cc1

InChI Key InChIKey=ZDIROZZUYKRUKS-NRFANRHFSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074166   

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074166(CHEMBL349390 | N-{4-[({(S)-1-[2-(5-[1,2,4]Triazol-...)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H]-5-HT binding from the cloned human 5-hydroxytryptamine 1D receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074166(CHEMBL349390 | N-{4-[({(S)-1-[2-(5-[1,2,4]Triazol-...)
Affinity DataIC50:  165nMAssay Description:Displacement of [3H]-5-HT binding from the cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074166(CHEMBL349390 | N-{4-[({(S)-1-[2-(5-[1,2,4]Triazol-...)
Affinity DataEC50:  10nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed