BDBM50075108 2-(2-chlorophenyl)-2-(4-cyanophenylcarboxamido)-1,1-dimethylpropanoic anhydride::CHEMBL338962

SMILES CC(C)(C(NC(=O)c1ccc(cc1)C#N)c1ccccc1Cl)C(=O)OC(=O)C(C)(C)C(NC(=O)c1ccc(cc1)C#N)c1ccccc1Cl

InChI Key InChIKey=GCAVMNHOWDAVHA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50075108   

TargetSerine protease 1(Homo sapiens (Human))
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075108(2-(2-chlorophenyl)-2-(4-cyanophenylcarboxamido)-1,...)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibitory activity against porcine pancreatic trypsin (TRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075108(2-(2-chlorophenyl)-2-(4-cyanophenylcarboxamido)-1,...)
Affinity DataIC50:  140nMAssay Description:Inhibitory activity against human leukocyte cathepsin G (h-CG)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075108(2-(2-chlorophenyl)-2-(4-cyanophenylcarboxamido)-1,...)
Affinity DataIC50:  250nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075108(2-(2-chlorophenyl)-2-(4-cyanophenylcarboxamido)-1,...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50075108(2-(2-chlorophenyl)-2-(4-cyanophenylcarboxamido)-1,...)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibitory activity against human chymase (h-chymase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed