BDBM50075673 2-(4-Chloro-3-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-cyclopent-2-enone::CHEMBL23175

SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccc(Cl)c(F)c1

InChI Key InChIKey=GAAWMIACGLOHRF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075673   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075673(2-(4-Chloro-3-fluoro-phenyl)-3-(4-methanesulfonyl-...)
Affinity DataIC50:  700nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 1 in U937 microsomes .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075673(2-(4-Chloro-3-fluoro-phenyl)-3-(4-methanesulfonyl-...)
Affinity DataIC50:  15nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075673(2-(4-Chloro-3-fluoro-phenyl)-3-(4-methanesulfonyl-...)
Affinity DataIC50:  150nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075673(2-(4-Chloro-3-fluoro-phenyl)-3-(4-methanesulfonyl-...)
Affinity DataIC50:  100nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 1 (hCOX-1) in the human whole blood assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed