BDBM50075695 6,7-Dimethoxy-4-(3,4,5-trimethoxy-phenyl)-3H-naphtho[2,3-c]furan-1-one::CHEMBL24323

SMILES COc1cc(cc(OC)c1OC)-c1c2COC(=O)c2cc2cc(OC)c(OC)cc12

InChI Key InChIKey=WBJONNSPSBKOSD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075695   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50075695(6,7-Dimethoxy-4-(3,4,5-trimethoxy-phenyl)-3H-napht...)
Affinity DataIC50:  68nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50075695(6,7-Dimethoxy-4-(3,4,5-trimethoxy-phenyl)-3H-napht...)
Affinity DataIC50:  840nMAssay Description:Inhibitory activity against phosphodiesterase 3 (PDE 3) isolated from cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50075695(6,7-Dimethoxy-4-(3,4,5-trimethoxy-phenyl)-3H-napht...)
Affinity DataIC50:  430nMAssay Description:Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed