BDBM50075763 4-[5-(4-Chloro-phenyl)-3-(2,6-dipropoxy-phenyl)-1H-pyrrol-2-yl]-pyridine::CHEMBL347462

SMILES CCCOc1cccc(OCCC)c1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1

InChI Key InChIKey=RYGNZEQECYUPSL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075763   

TargetGlucagon receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075763(4-[5-(4-Chloro-phenyl)-3-(2,6-dipropoxy-phenyl)-1H...)
Affinity DataIC50: >3.00E+3nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of 125 I-glucagon to the murine glucagon receptor (mGLUR) expressed on ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075763(4-[5-(4-Chloro-phenyl)-3-(2,6-dipropoxy-phenyl)-1H...)
Affinity DataIC50:  290nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the human glucagon receptor (GGR) expressed on CH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075763(4-[5-(4-Chloro-phenyl)-3-(2,6-dipropoxy-phenyl)-1H...)
Affinity DataIC50:  670nMAssay Description:Binding affinity determined by reduction in binding of 125 I-glucagon to the human glucagon receptor expressed on CHO cells in absence of Mg+2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075763(4-[5-(4-Chloro-phenyl)-3-(2,6-dipropoxy-phenyl)-1H...)
Affinity DataIC50:  40nMAssay Description:Binding affinity determined by reduction in binding of 125 I-glucagon to the human glucagon receptor expressed on CHO cells in absence of Mg+2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed