BDBM50076922 1,11-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylamino)-12-(3,4,5-trihydroxy-6-hydroxymethyltetrahydro-2H-2-pyranyl)-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione::CHEMBL277008
SMILES OCC(CO)NN1C(=O)c2c(C1=O)c1c3cccc(O)c3n(C3OC(CO)C(O)C(O)C3O)c1c1[nH]c3c(O)cccc3c21
InChI Key InChIKey=GCRUJJZDHHVZTG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50076922
TargetProtein kinase C alpha type(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:In vitro activity evaluated against protein kinase C (using histone II-As as a substrate)More data for this Ligand-Target Pair
Affinity DataEC50: 580nMAssay Description:In vitro activity against topoisomerase-I mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:In vitro activity against Epidermal growth factor receptor (using poly(Glu4Tyr1) as a substrate)More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro activity against topoisomerase-2 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
Affinity DataEC50: 580nMAssay Description:In vitro inhibition of Topoisomerase I-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
TargetO94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:In vitro inhibition of PKC mediated DNA cleavage.More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-binding protein 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro inhibition of Topoisomerase II-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair