BDBM50077372 CHEMBL292128::[(R)-2-(5-Isoxazol-3-yl-thiophene-2-sulfonyl)-1,2,3,4-tetrahydro-isoquinolin-3-yl]-oxo-acetic acid

SMILES OC(=O)C(=O)[C@H]1Cc2ccccc2CN1S(=O)(=O)c1ccc(s1)-c1ccon1

InChI Key InChIKey=SRXJKOWUSBFUNU-CQSZACIVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50077372   

TargetNeutrophil collagenase(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077372(CHEMBL292128 | [(R)-2-(5-Isoxazol-3-yl-thiophene-2...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed