BDBM50077885 CHEMBL3417057::US9611229, 4

SMILES C(CN1CCCCC1)Nc1cn(Cc2ccccc2)nn1

InChI Key InChIKey=XXDRNLWHVANHLR-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077885   

TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
Laboratorios Del Dr. Esteve

US Patent
LigandPNGBDBM50077885(CHEMBL3417057 | US9611229, 4)
Affinity DataKi:  48.5nMAssay Description:Brain membrane preparation and binding assays for the 61-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y. For...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Esteve

Curated by ChEMBL
LigandPNGBDBM50077885(CHEMBL3417057 | US9611229, 4)
Affinity DataKi:  49nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor transfected in HEK293 cells after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Esteve

Curated by ChEMBL
LigandPNGBDBM50077885(CHEMBL3417057 | US9611229, 4)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed