BDBM50077977 4-(2,4-diphenyl-1H-imidazol-5-yl)-N-methylpyrimidin-2-amine::CHEMBL67633::[4-(2,5-Diphenyl-3H-imidazol-4-yl)-pyrimidin-2-yl]-methyl-amine

SMILES CNc1nccc(n1)-c1nc([nH]c1-c1ccccc1)-c1ccccc1

InChI Key InChIKey=QMCGWRVMZPNHKW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077977   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077977(4-(2,4-diphenyl-1H-imidazol-5-yl)-N-methylpyrimidi...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibitory activity against recombinant human RAF proto-oncogene serine/threonine-protein kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077977(4-(2,4-diphenyl-1H-imidazol-5-yl)-N-methylpyrimidi...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077977(4-(2,4-diphenyl-1H-imidazol-5-yl)-N-methylpyrimidi...)
Affinity DataIC50:  175nMAssay Description:Inhibition of c-Jun N-terminal kinase 2-alpha 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed