BDBM50078151 CHEMBL3417691

SMILES Cc1ccccc1-c1cccc2c(CCCOc3cccc4ccccc34)c([nH]c12)C(O)=O

InChI Key InChIKey=YXFMHHXNIYGNKK-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50078151   

TargetAlbumin(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078151(CHEMBL3417691)
Affinity DataKi: <30nMAssay Description:Displacement of probe S1 from recombinant human serum albumin domain 3 after 5 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078151(CHEMBL3417691)
Affinity DataKi:  35nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant human MCL1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078151(CHEMBL3417691)
Affinity DataKi:  8.60E+3nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant human MCL1 by fluorescence polarization assay in presence of 1% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078151(CHEMBL3417691)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of N-terminal GST-tagged-Mcl1 (E171 to G327) (unknown origin) expressed in Escherichia coli using HyLite Fluor 647-labeled Bim peptide C a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed