BDBM50078379 CHEMBL3414920

SMILES C[C@H](c1nnc2c(F)cc(cn12)-c1cc(C)ns1)c1ccc2ncccc2c1

InChI Key InChIKey=PGYRRMODSKSGTC-ZDUSSCGKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50078379   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50078379(CHEMBL3414920)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant c-Met kinase domain (unknown origin) incubated for 30 mins using gastrin peptide substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50078379(CHEMBL3414920)
Affinity DataIC50:  12nMAssay Description:Inhibition of HGF-stimulated c-Met autophosphorylation in serum starved human PC3 cells pre-incubated for 1 hr followed by human recombinant HGF stim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed