BDBM50078530 4-Oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]quinoxaline-2-carboxylic acid ethyl ester::CHEMBL86164::ethyl 4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]quinoxaline-2-carboxylate

SMILES CCOC(=O)c1nc2n(n1)c1ccccc1[nH]c2=O

InChI Key InChIKey=PTTFPEJFOCLEGM-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50078530   

TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50078530(4-Oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]quinoxalin...)
Affinity DataKi:  70.8nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Universita' Di Firenze

Curated by ChEMBL
LigandPNGBDBM50078530(4-Oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]quinoxalin...)
Affinity DataKi:  1.67E+4nMAssay Description:Binding affinity towards N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes using [3H]-glycine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Universita' Di Firenze

Curated by ChEMBL
LigandPNGBDBM50078530(4-Oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]quinoxalin...)
Affinity DataKi:  1.67E+4nMAssay Description:Binding selectivity towards N-methyl-D-aspartate glutamate receptor 1 was determined by using [3H]- glycine/NMDAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Universita' Di Firenze

Curated by ChEMBL
LigandPNGBDBM50078530(4-Oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]quinoxalin...)
Affinity DataEC50:  6.90E+4nMAssay Description:Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed