BDBM50078565 (S)-2-[(Biphenyl-4-sulfonyl)-isobutyl-amino]-N-hydroxy-4-methylsulfanyl-butyramide::CHEMBL47728

SMILES CSCC[C@H](N(CC(C)C)S(=O)(=O)c1ccc(cc1)-c1ccccc1)C(=O)NO

InChI Key InChIKey=XXNCZTSFXIANIO-FQEVSTJZSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50078565   

TargetCollagenase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078565((S)-2-[(Biphenyl-4-sulfonyl)-isobutyl-amino]-N-hyd...)
Affinity DataIC50:  3nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078565((S)-2-[(Biphenyl-4-sulfonyl)-isobutyl-amino]-N-hyd...)
Affinity DataIC50:  156nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078565((S)-2-[(Biphenyl-4-sulfonyl)-isobutyl-amino]-N-hyd...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078565((S)-2-[(Biphenyl-4-sulfonyl)-isobutyl-amino]-N-hyd...)
Affinity DataIC50:  37nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078565((S)-2-[(Biphenyl-4-sulfonyl)-isobutyl-amino]-N-hyd...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed