BDBM50078638 CHEMBL3415182
SMILES: Cc1cn(CCn2cnc(-c3cnn(C)c3)c2-c2ccc(cc2)C#N)nn1
InChI Key: InChIKey=YPRKVQKJNRKXFN-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bromodomain adjacent to zinc finger domain protein 2B (Homo sapiens (Human)) | BDBM50078638![]() (CHEMBL3415182) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Displacement of H3K14Ac from BAZ2B (unknown origin) preincubated for 30 mins with non-biotinylated peptide followed by addition of biotinylated pepti... | J Med Chem 58: 2553-9 (2015) Article DOI: 10.1021/jm501963e BindingDB Entry DOI: 10.7270/Q2V69M9B | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Bromodomain adjacent to zinc finger domain protein 2A (Homo sapiens (Human)) | BDBM50078638![]() (CHEMBL3415182) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of BAZ2A (unknown origin) after 30 mins by AlphaScreen assay | J Med Chem 58: 2553-9 (2015) Article DOI: 10.1021/jm501963e BindingDB Entry DOI: 10.7270/Q2V69M9B | |||||||||||
More data for this Ligand-Target Pair |