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BDBM50078639 CHEMBL3415181

SMILES: Cc1cn(CCn2cncc2-c2ccc(cc2)C#N)nn1

InChI Key: InChIKey=LYXPBOVOLCOITB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50078639   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bromodomain adjacent to zinc finger domain protein 2B


(Homo sapiens (Human))
BDBM50078639
PNG
(CHEMBL3415181)
Show SMILES Cc1cn(CCn2cncc2-c2ccc(cc2)C#N)nn1
Show InChI InChI=1S/C15H14N6/c1-12-10-21(19-18-12)7-6-20-11-17-9-15(20)14-4-2-13(8-16)3-5-14/h2-5,9-11H,6-7H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



The Institute of Cancer Research

Curated by ChEMBL


Assay Description
Displacement of H3K14Ac from BAZ2B (unknown origin) preincubated for 30 mins with non-biotinylated peptide followed by addition of biotinylated pepti...


J Med Chem 58: 2553-9 (2015)


Article DOI: 10.1021/jm501963e
BindingDB Entry DOI: 10.7270/Q2V69M9B
More data for this
Ligand-Target Pair
Bromodomain adjacent to zinc finger domain protein 2A


(Homo sapiens (Human))
BDBM50078639
PNG
(CHEMBL3415181)
Show SMILES Cc1cn(CCn2cncc2-c2ccc(cc2)C#N)nn1
Show InChI InChI=1S/C15H14N6/c1-12-10-21(19-18-12)7-6-20-11-17-9-15(20)14-4-2-13(8-16)3-5-14/h2-5,9-11H,6-7H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



The Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of BAZ2A (unknown origin) after 30 mins by AlphaScreen assay


J Med Chem 58: 2553-9 (2015)


Article DOI: 10.1021/jm501963e
BindingDB Entry DOI: 10.7270/Q2V69M9B
More data for this
Ligand-Target Pair