BDBM50079432 4-{2-[2-Carboxy-2-(4,6-dimethyl-pyrimidin-2-yloxy)-1,1-diphenyl-ethoxy]-ethyl}-benzoic acid::CHEMBL101742

SMILES Cc1cc(C)nc(OC(C(O)=O)C(OCCc2ccc(cc2)C(O)=O)(c2ccccc2)c2ccccc2)n1

InChI Key InChIKey=JNFNRBRGVCBLHK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50079432   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079432(4-{2-[2-Carboxy-2-(4,6-dimethyl-pyrimidin-2-yloxy)...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079432(4-{2-[2-Carboxy-2-(4,6-dimethyl-pyrimidin-2-yloxy)...)
Affinity DataKi:  115nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed