BDBM50079457 1-Methyl-1,2,3,4,5,6-hexahydro-[2,3']bipyridinyl::CHEMBL102246::US10667515, Compound N-methyl-anabasine

SMILES CN1CCCCC1c1cccnc1

InChI Key InChIKey=WHAIHNKQZOMXJJ-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50079457   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Targacept

Curated by ChEMBL
LigandPNGBDBM50079457(1-Methyl-1,2,3,4,5,6-hexahydro-[2,3']bipyridinyl |...)
Affinity DataKi:  450nMAssay Description:Binding affinity at heteropentameric Nicotinic acetylcholine receptor alpha4-beta2 subtype using [3H]-bungarotoxin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept

Curated by ChEMBL
LigandPNGBDBM50079457(1-Methyl-1,2,3,4,5,6-hexahydro-[2,3']bipyridinyl |...)
Affinity DataKi:  9.70E+3nMAssay Description:Binding affinity at homopentameric Nicotinic acetylcholine receptor alpha7 subtype using [3H]-S-(-)-nicotine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetResistance to inhibitors of cholinesterase protein 3(Pig roundworm)
Iowa State University Research Foundation

US Patent
LigandPNGBDBM50079457(1-Methyl-1,2,3,4,5,6-hexahydro-[2,3']bipyridinyl |...)
Affinity DataEC50: <1.00E+5nMAssay Description:Nematode eggs are isolated from fresh feces by centrifugation and flotation. The eggs are washed and inspected to confirm embryonation has not starte...More data for this Ligand-Target Pair
In DepthDetails US Patent