BDBM50079579 CHEMBL3417505

SMILES C[C@H](COc1ccc(cc1)C1=NNC(=O)C2CC12)CN1CCC[C@H]1C

InChI Key InChIKey=ADTARRIQWGUIIA-BULQSVBWSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50079579   

TargetHistamine H3 receptor(Homo sapiens (Human))
Teva Global R & D.

Curated by ChEMBL
LigandPNGBDBM50079579(CHEMBL3417505)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Teva Global R & D.

Curated by ChEMBL
LigandPNGBDBM50079579(CHEMBL3417505)
Affinity DataKi:  9.80nMAssay Description:Binding affinity to rat histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Teva Global R & D.

Curated by ChEMBL
LigandPNGBDBM50079579(CHEMBL3417505)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Teva Global R & D.

Curated by ChEMBL
LigandPNGBDBM50079579(CHEMBL3417505)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Teva Global R & D.

Curated by ChEMBL
LigandPNGBDBM50079579(CHEMBL3417505)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human ERG by patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Teva Global R & D.

Curated by ChEMBL
LigandPNGBDBM50079579(CHEMBL3417505)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Teva Global R & D.

Curated by ChEMBL
LigandPNGBDBM50079579(CHEMBL3417505)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Teva Global R & D.

Curated by ChEMBL
LigandPNGBDBM50079579(CHEMBL3417505)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed