BDBM50079790 (S)-2-{[(2S,4S)-1-((E)-(2S,5R)-5-Amino-2-isopropyl-6-mercapto-hex-3-enoyl)-4-phenoxy-pyrrolidine-2-carbonyl]-amino}-4-methylsulfanyl-butyric acid methyl ester with di( TFA)::CHEMBL305772
SMILES COC(=O)[C@H](CCSC)NC(=O)[C@@H]1C[C@@H](CN1C(=O)[C@H](\C=C\[C@@H](N)CS)C(C)C)Oc1ccccc1
InChI Key InChIKey=YHCMNPICRRIROW-UEIALUENSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50079790
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Mus musculus)
Eisai Research Institute
Curated by ChEMBL
Eisai Research Institute
Curated by ChEMBL
Affinity DataIC50: 840nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair