BDBM50079790 (S)-2-{[(2S,4S)-1-((E)-(2S,5R)-5-Amino-2-isopropyl-6-mercapto-hex-3-enoyl)-4-phenoxy-pyrrolidine-2-carbonyl]-amino}-4-methylsulfanyl-butyric acid methyl ester with di( TFA)::CHEMBL305772

SMILES COC(=O)[C@H](CCSC)NC(=O)[C@@H]1C[C@@H](CN1C(=O)[C@H](\C=C\[C@@H](N)CS)C(C)C)Oc1ccccc1

InChI Key InChIKey=YHCMNPICRRIROW-UEIALUENSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50079790   

LigandPNGBDBM50079790((S)-2-{[(2S,4S)-1-((E)-(2S,5R)-5-Amino-2-isopropyl...)
Affinity DataIC50:  840nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed