BDBM50079809 (S)-2-{[(2S,4S)-1-((E)-(R)-4-Amino-5-mercapto-pent-2-enyl)-4-(5,6,7,8-tetrahydro-naphthalen-1-yloxy)-pyrrolidine-2-carbonyl]-amino}-4-methylsulfanyl-butyric acid with di( TFA)::CHEMBL63366
SMILES CSCC[C@H](NC(=O)[C@@H]1C[C@@H](CN1C\C=C\[C@@H](N)CS)Oc1cccc2CCCCc12)C(O)=O
InChI Key InChIKey=RSBRCAAERNSFPY-AYPLTYEISA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50079809
TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute
Curated by ChEMBL
Eisai Research Institute
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute
Curated by ChEMBL
Eisai Research Institute
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair