BDBM50079809 (S)-2-{[(2S,4S)-1-((E)-(R)-4-Amino-5-mercapto-pent-2-enyl)-4-(5,6,7,8-tetrahydro-naphthalen-1-yloxy)-pyrrolidine-2-carbonyl]-amino}-4-methylsulfanyl-butyric acid with di( TFA)::CHEMBL63366

SMILES CSCC[C@H](NC(=O)[C@@H]1C[C@@H](CN1C\C=C\[C@@H](N)CS)Oc1cccc2CCCCc12)C(O)=O

InChI Key InChIKey=RSBRCAAERNSFPY-AYPLTYEISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50079809   

LigandPNGBDBM50079809((S)-2-{[(2S,4S)-1-((E)-(R)-4-Amino-5-mercapto-pent...)
Affinity DataIC50:  89nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50079809((S)-2-{[(2S,4S)-1-((E)-(R)-4-Amino-5-mercapto-pent...)
Affinity DataIC50:  47nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed