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BDBM50080267 2,5-Bis-(4,6-dimethyl-pyridin-2-ylcarbamoyl)-terephthalic acid::CHEMBL79152

SMILES: Cc1cc(C)nc(NC(=O)c2cc(C(O)=O)c(cc2C(O)=O)C(=O)Nc2cc(C)cc(C)n2)c1

InChI Key: InChIKey=IITAYGVKEQCVLG-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50080267   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50080267
PNG
(2,5-Bis-(4,6-dimethyl-pyridin-2-ylcarbamoyl)-terep...)
Show SMILES Cc1cc(C)nc(NC(=O)c2cc(C(O)=O)c(cc2C(O)=O)C(=O)Nc2cc(C)cc(C)n2)c1
Show InChI InChI=1S/C24H22N4O6/c1-11-5-13(3)25-19(7-11)27-21(29)15-9-18(24(33)34)16(10-17(15)23(31)32)22(30)28-20-8-12(2)6-14(4)26-20/h5-10H,1-4H3,(H,31,32)(H,33,34)(H,25,27,29)(H,26,28,30)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 6.00E+4n/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against Lck SH2 domain


Bioorg Med Chem Lett 9: 2403-6 (1999)


Article DOI: 10.1016/s0960-894x(99)00403-5
BindingDB Entry DOI: 10.7270/Q2Z89BK7
More data for this
Ligand-Target Pair