BDBM50039177 3-[Bis-(4-chloro-phenyl)-methoxy]-8-methyl-8-aza-bicyclo[3.2.1]octane; hydrochloride::CHEMBL119664::CHEMBL541825
SMILES CN1C2CCC1CC(C2)OC(c1ccc(Cl)cc1)c1ccc(Cl)cc1
InChI Key InChIKey=DAAKBMHWKLVSKY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50039177
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 17.5nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat brainMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of [3H]WIN-35428 binding to the dopamine transporter in rat caudate putamen tissue.More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Binding affinity at dopamine transporter in rat brain by [3H]WIN-35428 displacement.More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Compound was evaluated for its ability to displace [3H]WIN-35428 binding in rat caudate-putamenMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Binding affinity for dopamine transporter was determined in vitro in rat brain using [3H]WIN-35428 s radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 23.4nMAssay Description:Ability of compound to inhibit dopamine uptake of receptor was determinedMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 40.6nMAssay Description:Displacement of [3H]pirenzepine from M1 receptor in Sprague-Dawley rat brainMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 47.9nMAssay Description:Binding affinity for muscarinic m1 receptor was determined in vitro in rat brain using [3H]pirenzepine as radioligand.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 47.9nMAssay Description:Binding affinity at muscarinic M1 receptor in rat brain by [3H]pirenzepine displacement.More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 220nMAssay Description:Binding affinity at dopamine receptor D3More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 1.64E+3nMAssay Description:Binding affinity at serotonin transporter in rat brain by [3H]-citalopram displacement.More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 1.64E+3nMAssay Description:Binding affinity for serotonin transporter was determined in vitro in rat brain using [3H]citalopram as radioligand.More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 1.64E+3nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 2.98E+3nMAssay Description:Binding affinity for norepinephrine transporter in rat brain using [3H]-nisoxatine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2.98E+3nMAssay Description:Displacement of [3H]nisoxetine from norepinephrine transporter (NET) of rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 2.98E+3nMAssay Description:Displacement of [3H]nisoxetine from NET in Sprague-Dawley rat brainMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of [3H]dopamine uptake in rat caudate putamen tissue.More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataIC50: 23.4nMAssay Description:Inhibition of [3H]dopamine uptake at DAT in Sprague-Dawley rat brainMore data for this Ligand-Target Pair