BDBM50080728 3-{[(4-aminophenyl)sulfonyl]amino}benzenesulfonamide::4-amino-N-(3-sulfamoylphenyl)benzenesulfonamide::4-amino-bis-benzenesulfonamide::CHEMBL14182

SMILES Nc1ccc(cc1)S(=O)(=O)Nc1cccc(c1)S(N)(=O)=O

InChI Key InChIKey=BYERREGDQUCYJP-UHFFFAOYSA-N

Data  15 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50080728   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50080728(3-{[(4-aminophenyl)sulfonyl]amino}benzenesulfonami...)
Affinity DataKi:  0.111nMAssay Description:Inhibition of human CA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50080728(3-{[(4-aminophenyl)sulfonyl]amino}benzenesulfonami...)
Affinity DataKi:  9nMAssay Description:Inhibitory activity against human carbonic anhydrase II (CA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50080728(3-{[(4-aminophenyl)sulfonyl]amino}benzenesulfonami...)
Affinity DataKi:  9nMAssay Description:Inhibitory activity against human recombinant carbonic anhydrase II (CA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50080728(3-{[(4-aminophenyl)sulfonyl]amino}benzenesulfonami...)
Affinity DataKi:  9nMAssay Description:Inhibition of human carbonic anhydrase II (hCA II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50080728(3-{[(4-aminophenyl)sulfonyl]amino}benzenesulfonami...)
Affinity DataKi:  30nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50080728(3-{[(4-aminophenyl)sulfonyl]amino}benzenesulfonami...)
Affinity DataKi:  44nMAssay Description:Inhibitory activity against human recombinant carbonic anhydrase I (CA1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50080728(3-{[(4-aminophenyl)sulfonyl]amino}benzenesulfonami...)
Affinity DataKi:  44nMAssay Description:Inhibitory activity against human carbonic anhydrase I (CA1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50080728(3-{[(4-aminophenyl)sulfonyl]amino}benzenesulfonami...)
Affinity DataKi:  44nMAssay Description:Inhibition of human carbonic anhydrase I (CAI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50080728(3-{[(4-aminophenyl)sulfonyl]amino}benzenesulfonami...)
Affinity DataKi:  44nMAssay Description:Inhibition of human CA1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
Universit£

Curated by ChEMBL
LigandPNGBDBM50080728(3-{[(4-aminophenyl)sulfonyl]amino}benzenesulfonami...)
Affinity DataKi:  53nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), isolated from bovine lung microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
Universit£

Curated by ChEMBL
LigandPNGBDBM50080728(3-{[(4-aminophenyl)sulfonyl]amino}benzenesulfonami...)
Affinity DataKi:  53nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), isolated from bovine lung microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
Universit£

Curated by ChEMBL
LigandPNGBDBM50080728(3-{[(4-aminophenyl)sulfonyl]amino}benzenesulfonami...)
Affinity DataKi:  53nMAssay Description:Inhibition of bovine carbonic anhydrase IV from bovine lung microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
Universit£

Curated by ChEMBL
LigandPNGBDBM50080728(3-{[(4-aminophenyl)sulfonyl]amino}benzenesulfonami...)
Affinity DataKi:  53nMAssay Description:Inhibition of bovine CA4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50080728(3-{[(4-aminophenyl)sulfonyl]amino}benzenesulfonami...)
Affinity DataKi:  95nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50080728(3-{[(4-aminophenyl)sulfonyl]amino}benzenesulfonami...)
Affinity DataKi:  1.11E+8nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed