BDBM50081107 4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benzoimidazole-2-thione::CHEMBL89037

SMILES Clc1cc(OCCNCc2ccccc2)c2[nH]c(=S)[nH]c2c1

InChI Key InChIKey=HMFWWORRYDWEDS-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50081107   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081107(4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benz...)
Affinity DataKi:  0.210nMAssay Description:Inhibition of [3H]-quinpirole binding to rat striatal membrane Dopamine receptor D2 without GTP and sodiumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081107(4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benz...)
Affinity DataKi:  4.5nMAssay Description:Inhibtion of [3H]-spiperone binding to rat striatal membrane Dopamine receptor D2 low affinity without GTP and sodiumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081107(4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benz...)
Affinity DataKi:  6.5nMAssay Description:Inihibition of [3H]-spiperone binding to human Dopamine receptor D2 in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081107(4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benz...)
Affinity DataKi:  11nMAssay Description:Inhibition of [3H]-spiperone binding to human Dopamine receptor D4.4 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081107(4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benz...)
Affinity DataKi:  12nMAssay Description:Inhibition of [3H]-spiperone binding to human Dopamine receptor D3 in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed