BDBM50081629 2-{[1-(5-Methanesulfonylamino-1H-indole-2-carbonyl)-piperidin-4-yl]-methyl-amino}-nicotinic acid methyl ester::CHEMBL130177

SMILES COC(=O)c1cccnc1N(C)C1CCN(CC1)C(=O)c1cc2cc(NS(C)(=O)=O)ccc2[nH]1

InChI Key InChIKey=VUIHMLIDUYCGNJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50081629   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50081629(2-{[1-(5-Methanesulfonylamino-1H-indole-2-carbonyl...)
Affinity DataIC50:  250nMAssay Description:Inhibition of Reverse transcriptase (Wild Type) with poly(rA)600:oligo(dT)10 template primerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50081629(2-{[1-(5-Methanesulfonylamino-1H-indole-2-carbonyl...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of Reverse transcriptase (P236L) using poly(rA)600:oligo(dT)10 as template primer.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50081629(2-{[1-(5-Methanesulfonylamino-1H-indole-2-carbonyl...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of Reverse transcriptase (Y181C) using poly(rA)600:oligo(dT)10 as template primer.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed