BDBM50081852 (2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-methylnaphthalene-1-sulfonamido)methyl)-4-oxo-4-(piperidin-1-yl)butanamide::(2R,3R)-3-Cyclopentylmethyl-N-hydroxy-2-{[methyl-(naphthalene-1-sulfonyl)-amino]-methyl}-4-oxo-4-piperidin-1-yl-butyramide::CHEMBL97936

SMILES CN(C[C@@H]([C@@H](CC1CCCC1)C(=O)N1CCCCC1)C(=O)NO)S(=O)(=O)c1cccc2ccccc12

InChI Key InChIKey=FCGVXISUYVDDPU-RPWUZVMVSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50081852   

TargetNeutrophil collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081852((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  4nMAssay Description:Inhibition of HNC MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081852((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Strom-1 MMP-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081852((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  6nMAssay Description:Inhibition of HFC MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081852((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Gel-A MMP-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081852((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  4nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081852((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  50nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50081852((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081852((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  50nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50081852((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  8nMAssay Description:Inhibition of Coll-3 MMP-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed