BDBM50082027 2-Chloro-N-{3-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dihydro-quinolin-3-yl)-phenoxy]-phenyl}-acetamide::CHEMBL138208

SMILES Oc1c(-c2cccc(Oc3cccc(NC(=O)CCl)c3)c2)c(=O)[nH]c2cc(Cl)ccc12

InChI Key InChIKey=WKNUHBCPLHAZPT-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082027   

TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Université

Curated by ChEMBL
LigandPNGBDBM50082027(2-Chloro-N-{3-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dih...)
Affinity DataKi:  13.8nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50082027(2-Chloro-N-{3-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dih...)
Affinity DataIC50:  39nMAssay Description:Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed