BDBM50082419 1-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxyphenyl)urea::1-[2-Furan-2-yl-8-(3-phenyl-propyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-3-(4-methoxy-phenyl)-urea::CHEMBL139182

SMILES COc1ccc(NC(=O)Nc2nc3nn(CCCc4ccccc4)cc3c3nc(nn23)-c2ccco2)cc1

InChI Key InChIKey=OLJJUIWQSVLKJD-UHFFFAOYSA-N

Data  13 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50082419   

TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50082419(1-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4...)
Affinity DataKi:  19.8nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50082419(1-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4...)
Affinity DataKi:  20nMAssay Description:Displacement of [125]AB-MECA from human Adenosine A3 receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50082419(1-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4...)
Affinity DataKi:  40nMAssay Description:Binding affinity for human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50082419(1-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]-MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells; range 33-48More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50082419(1-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4...)
Affinity DataKi:  101nMAssay Description:Displacement of [3H]-SCH- 58261 from human adenosine A2A receptor expressed in CHO cells; range 880-1160More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50082419(1-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4...)
Affinity DataKi:  251nMAssay Description:Displacement of [3H]-DPCPX from human Adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50082419(1-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4...)
Affinity DataKi:  251nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO cells; range 221-286More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50082419(1-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4...)
Affinity DataKi:  802nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A2b receptor expressed in CHO cells; range 719-895More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50082419(1-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4...)
Affinity DataKi:  1.01E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50082419(1-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4...)
Affinity DataKi:  1.02E+3nMAssay Description:Displacement of specific [3H]-SCH- 58261 binding at human Adenosine A2A receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50082419(1-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4...)
Affinity DataKi:  1.51E+3nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50082419(1-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-SCH- 58261 from Adenosine A2A receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50082419(1-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4...)
Affinity DataKi:  3.98E+4nMAssay Description:Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50082419(1-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration as antagonistic activity against cAMP generation inhibited by IB-MECA in CHO cell membranes transfected with human A3 recept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed