BDBM50082884 1-{(S)-5-[4-(2-Carbamoyl-phenyl)-piperazin-1-yl]-4-methyl-pentyl}-6-(3,4-difluoro-phenyl)-2,4-dimethyl-1,6-dihydro-pyrimidine-5-carboxylic acid methyl ester::CHEMBL358313

SMILES COC(=O)C1=C(C)N=C(C)N(CCC[C@H](C)CN2CCN(CC2)c2ccccc2C(N)=O)C1c1ccc(F)c(F)c1

InChI Key InChIKey=BLFCXMMGSUUVCS-OORIHMLWSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082884   

TargetAlpha-1A adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082884(1-{(S)-5-[4-(2-Carbamoyl-phenyl)-piperazin-1-yl]-4...)
Affinity DataKi:  3.5nMAssay Description:Binding affinity against Alpha-1A adrenergic receptor (recombinant human receptor) using [3H]prazosin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082884(1-{(S)-5-[4-(2-Carbamoyl-phenyl)-piperazin-1-yl]-4...)
Affinity DataKi:  810nMAssay Description:Binding affinity against Alpha-1B adrenergic receptor (recombinant human receptor) using [3H]prazosin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082884(1-{(S)-5-[4-(2-Carbamoyl-phenyl)-piperazin-1-yl]-4...)
Affinity DataKi:  1.70E+3nMAssay Description:Binding affinity against Alpha-1D adrenergic receptor (recombinant human receptor) using [3H]-prazosin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed