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BDBM50083285 1-Adamantan-1-yl-3-{2-[4-(3-chloro-phenyl)-piperazin-1-yl]-ethyl}-urea::CHEMBL149887

SMILES: Clc1cccc(c1)N1CCN(CCNC(=O)NC23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1

InChI Key: InChIKey=YNPAKXJCEFCUJW-NWKQVAMWSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083285   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50083285
PNG
(1-Adamantan-1-yl-3-{2-[4-(3-chloro-phenyl)-piperaz...)
Show SMILES Clc1cccc(c1)N1CCN(CCNC(=O)NC23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1
Show InChI InChI=1S/C23H33ClN4O/c24-20-2-1-3-21(13-20)28-8-6-27(7-9-28)5-4-25-22(29)26-23-14-17-10-18(15-23)12-19(11-17)16-23/h1-3,13,17-19H,4-12,14-16H2,(H2,25,26,29)/t17-,18+,19-,23?
KEGG

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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
61n/an/an/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
Antagonist activity against rat hippocampal tissue 5-hydroxytryptamine 1A receptor


J Med Chem 42: 5077-94 (2000)


Article DOI: 10.1021/jm9806704
BindingDB Entry DOI: 10.7270/Q2C82B0P
More data for this
Ligand-Target Pair