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BDBM50083301 1-Adamantan-1-yl-3-{3-[4-(3-chloro-phenyl)-piperazin-1-yl]-propyl}-urea; dihydrochloride::CHEMBL555639

SMILES: Clc1cccc(c1)N1CCN(CCCNC(=O)NC23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1

InChI Key: InChIKey=XJQLADRNETYCAD-GUHGBLDKSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083301   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50083301
PNG
(1-Adamantan-1-yl-3-{3-[4-(3-chloro-phenyl)-piperaz...)
Show SMILES Clc1cccc(c1)N1CCN(CCCNC(=O)NC23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1
Show InChI InChI=1S/C24H35ClN4O/c25-21-3-1-4-22(14-21)29-9-7-28(8-10-29)6-2-5-26-23(30)27-24-15-18-11-19(16-24)13-20(12-18)17-24/h1,3-4,14,18-20H,2,5-13,15-17H2,(H2,26,27,30)/t18-,19+,20-,24?
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
45n/an/an/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
Antagonist activity against rat hippocampal tissue 5-hydroxytryptamine 1A receptor


J Med Chem 42: 5077-94 (2000)


Article DOI: 10.1021/jm9806704
BindingDB Entry DOI: 10.7270/Q2C82B0P
More data for this
Ligand-Target Pair