BDBM50084228 2-(diethylamino)-5-methyl-4H-thieno[2,3-d][1,3]oxazin-4-one::2-Diethylamino-5-methyl-thieno[2,3-d][1,3]oxazin-4-one::CHEMBL153631

SMILES CCN(CC)c1nc2scc(C)c2c(=O)o1

InChI Key InChIKey=GDEMQONFUDCKJA-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084228   

TargetNeutrophil elastase(Human)
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084228(2-(diethylamino)-5-methyl-4H-thieno[2,3-d][1,3]oxa...)
Affinity DataKi:  450nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBile salt-activated lipase(Bovine)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50084228(2-(diethylamino)-5-methyl-4H-thieno[2,3-d][1,3]oxa...)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibitory activity against bovine pancreatic CEase in presence of pNPB chromogenic substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Electric eel)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50084228(2-(diethylamino)-5-methyl-4H-thieno[2,3-d][1,3]oxa...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity AChE from Electrophorus electricus using ATCh substrate and DTNB by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeutrophil elastase(Human)
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084228(2-(diethylamino)-5-methyl-4H-thieno[2,3-d][1,3]oxa...)
Affinity DataKd:  5.50E+3nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed