BDBM50084293 (S)-2-(4'-chloro-biphenyl-4-sulfonylamino)-3-methyl-butyric acid::2-(4'-Chloro-biphenyl-4-sulfonylamino)-3-methyl-butyric acid::CHEMBL296196

SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Cl)cc1)C(O)=O

InChI Key InChIKey=PTONAIKVYGVBIS-INIZCTEOSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50084293   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50084293((S)-2-(4'-chloro-biphenyl-4-sulfonylamino)-3-methy...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human recombinant MMP9 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50084293((S)-2-(4'-chloro-biphenyl-4-sulfonylamino)-3-methy...)
Affinity DataIC50:  9nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50084293((S)-2-(4'-chloro-biphenyl-4-sulfonylamino)-3-methy...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50084293((S)-2-(4'-chloro-biphenyl-4-sulfonylamino)-3-methy...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50084293((S)-2-(4'-chloro-biphenyl-4-sulfonylamino)-3-methy...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50084293((S)-2-(4'-chloro-biphenyl-4-sulfonylamino)-3-methy...)
Affinity DataIC50:  48nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50084293((S)-2-(4'-chloro-biphenyl-4-sulfonylamino)-3-methy...)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50084293((S)-2-(4'-chloro-biphenyl-4-sulfonylamino)-3-methy...)
Affinity DataIC50:  7.50E+3nMAssay Description:In vitro inhibition of matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50084293((S)-2-(4'-chloro-biphenyl-4-sulfonylamino)-3-methy...)
Affinity DataIC50:  1.60E+4nMAssay Description:In vitro inhibition of matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50084293((S)-2-(4'-chloro-biphenyl-4-sulfonylamino)-3-methy...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50084293((S)-2-(4'-chloro-biphenyl-4-sulfonylamino)-3-methy...)
Affinity DataIC50:  48nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50084293((S)-2-(4'-chloro-biphenyl-4-sulfonylamino)-3-methy...)
Affinity DataIC50:  9nMAssay Description:In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50084293((S)-2-(4'-chloro-biphenyl-4-sulfonylamino)-3-methy...)
Affinity DataIC50:  6.50E+3nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed