BDBM50084665 CHEMBL115189::N*4*-(2,2-Dimethyl-1-methylcarbamoyl-propyl)-2,N*1*-dihydroxy-3-isobutyl-succinamide(Marimisant)

SMILES CNC(=O)C(NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C

InChI Key InChIKey=OCSMOTCMPXTDND-JKIOLJMWSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50084665   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50084665(CHEMBL115189 | N*4*-(2,2-Dimethyl-1-methylcarbamoy...)
Affinity DataIC50:  3nMAssay Description:Inhibition of matrix metalloprotease-9 (MMP-9).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50084665(CHEMBL115189 | N*4*-(2,2-Dimethyl-1-methylcarbamoy...)
Affinity DataIC50:  200nMAssay Description:Inhibition of matrix metalloprotease-3 (MMP-3).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50084665(CHEMBL115189 | N*4*-(2,2-Dimethyl-1-methylcarbamoy...)
Affinity DataIC50:  2nMAssay Description:Inhibition of matrix metalloprotease-8 (MMP-8).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50084665(CHEMBL115189 | N*4*-(2,2-Dimethyl-1-methylcarbamoy...)
Affinity DataIC50:  5nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50084665(CHEMBL115189 | N*4*-(2,2-Dimethyl-1-methylcarbamoy...)
Affinity DataIC50:  6nMAssay Description:Inhibition of matrix metalloprotease-2 (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50084665(CHEMBL115189 | N*4*-(2,2-Dimethyl-1-methylcarbamoy...)
Affinity DataIC50:  20nMAssay Description:Inhibition of matrix metalloprotease-7 (MMP-7).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed