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BDBM50084858 CHEMBL137298::Cyclohexanecarboxylic acid (2-{4-[2-(2-fluoro-ethoxy)-phenyl]-piperazin-1-yl}-ethyl)-pyridin-2-yl-amide

SMILES: FCCOc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1

InChI Key: InChIKey=AHQWOKUFGWQUMW-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50084858   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50084858
PNG
(CHEMBL137298 | Cyclohexanecarboxylic acid (2-{4-[2...)
Show SMILES FCCOc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1
Show InChI InChI=1S/C26H35FN4O2/c27-13-21-33-24-11-5-4-10-23(24)30-18-15-29(16-19-30)17-20-31(25-12-6-7-14-28-25)26(32)22-8-2-1-3-9-22/h4-7,10-12,14,22H,1-3,8-9,13,15-21H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.55n/an/an/an/an/an/a



University of Groningen

Curated by ChEMBL


Assay Description
In vitro affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT in rat hippocampus


J Med Chem 43: 432-9 (2000)


Article DOI: 10.1021/jm991088y
BindingDB Entry DOI: 10.7270/Q2513XFN
More data for this
Ligand-Target Pair