BDBM50085450 (3S,6S,8aS)-6-Hydroxy-6-methyl-5-oxo-octahydro-indolizine-3-carboxylic acid 4-carbamimidoyl-benzylamide; hydrochloride::CHEMBL542661

SMILES C[C@]1(O)CC[C@@H]2CC[C@H](N2C1=O)C(=O)NCc1ccc(cc1)C(N)=N

InChI Key InChIKey=GKFBOXZXQWZDSW-DEYYWGMASA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50085450   

TargetProthrombin(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50085450((3S,6S,8aS)-6-Hydroxy-6-methyl-5-oxo-octahydro-ind...)
Affinity DataKi:  125nMAssay Description:The compound was evaluated for binding affinity against ProthrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50085450((3S,6S,8aS)-6-Hydroxy-6-methyl-5-oxo-octahydro-ind...)
Affinity DataIC50:  270nMAssay Description:Compound was tested for inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50085450((3S,6S,8aS)-6-Hydroxy-6-methyl-5-oxo-octahydro-ind...)
Affinity DataIC50:  251nMAssay Description:Concentration required for 50 percent inhibition of ProthrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50085450((3S,6S,8aS)-6-Hydroxy-6-methyl-5-oxo-octahydro-ind...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was tested for inhibitory activity against Coagulation factor VIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed