BDBM50086104 4-[2-(1H-Indol-3-yl)-ethyl]-piperidine-1-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide::CHEMBL280000

SMILES COc1ccc(NC(=O)N2CCC(CCc3c[nH]c4ccccc34)CC2)cc1N1CCN(C)CC1

InChI Key InChIKey=MLYDWVQYHWPBIQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50086104   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50086104(4-[2-(1H-Indol-3-yl)-ethyl]-piperidine-1-carboxyli...)
Affinity DataIC50: >300nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex using [125I]-iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50086104(4-[2-(1H-Indol-3-yl)-ethyl]-piperidine-1-carboxyli...)
Affinity DataIC50:  200nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1D receptor in rat frontal cortex using [125I]-iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50086104(4-[2-(1H-Indol-3-yl)-ethyl]-piperidine-1-carboxyli...)
Affinity DataIC50:  120nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor in rat frontal cortex using [125I]-iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed