BDBM50086347 CHEMBL3426061
SMILES CNC(=O)[C@H]1CC[C@@H](CC1)Nc1nc(C)nc2c(cc(cc12)-c1cncs1)C(F)(F)F
InChI Key InChIKey=QADCFCAKUGGZJW-MQMHXKEQSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50086347
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mus musculus)
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of mouse recombinant CD38 extracellular domain expressed in CHO CGE cells assessed as NAD hydrolysis by fluorescence plate reader analysisMore data for this Ligand-Target Pair
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of human CD38 extracellular domain expressed in Pichia pastoris assessed as NAD hydrolysis by colorimetric-based assayMore data for this Ligand-Target Pair